Role of sentinel lymph node biopsy in patients with ductal carcinoma in situ and microinvasion
Identifieur interne : 004674 ( Main/Exploration ); précédent : 004673; suivant : 004675Role of sentinel lymph node biopsy in patients with ductal carcinoma in situ and microinvasion
Auteurs : Ansar Farooq [Niger] ; Mysore Chandrshekar [Royaume-Uni] ; Kieran HorganSource :
- Surgical Practice [ 1744-1625 ] ; 2012-05.
Abstract
Aim: Ductal carcinoma in situ with microinvasion (DCISMI) is characterized by one or more areas of focal invasion, 1 mm or less in diameter. While pure ductal carcinoma in situ (DCIS) does not have the potential to metastasize to regional nodes, the presence of microinvasion makes lymph node metastasis possible, leading to current guidelines recommending staging of the axilla with sentinel lymph node biopsy (SLNB). However, there are few studies looking at the risk of lymphatic spread in patients with DCISMI, and indications for axillary staging in such cases is controversial. The aim of the present study was to assess the prevalence of nodal metastasis in patients with DCISMI in order to help ascertain whether SLNB can be safely avoided in DCISMI.
Url:
DOI: 10.1111/j.1744-1633.2012.00588.x
Affiliations:
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<front><div type="abstract">Aim: Ductal carcinoma in situ with microinvasion (DCISMI) is characterized by one or more areas of focal invasion, 1 mm or less in diameter. While pure ductal carcinoma in situ (DCIS) does not have the potential to metastasize to regional nodes, the presence of microinvasion makes lymph node metastasis possible, leading to current guidelines recommending staging of the axilla with sentinel lymph node biopsy (SLNB). However, there are few studies looking at the risk of lymphatic spread in patients with DCISMI, and indications for axillary staging in such cases is controversial. The aim of the present study was to assess the prevalence of nodal metastasis in patients with DCISMI in order to help ascertain whether SLNB can be safely avoided in DCISMI.</div>
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